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EneSoothe® Repcomf oil
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  • EneSoothe® Repcomf oil

EneSoothe® Repcomf oil

INCI Name Olea Europaea (Olive) Fruit Extract, Artemisia Annua Extract, Chamomilla Recutita (Matricaria) Flower Extract, Citrus Grandis (Grapefruit) Fruit Extract, Caprylic/Capric Triglyceride, Hexyldecanol
Application Soothing and Anti-inflammation
Recommended use level 0.5~5.0%
Product Overview

EneSoothe® Repcomf Oil is a botanical soothing and barrier-repair oil designed to help skin cope with environmental stress. By targeting multiple inflammatory pathways, it helps reduce redness, soothe discomfort, and reinforce skin barrier resilience.

A Botanical Dialogue Between Comfort and Resilience

Across diverse ecosystems, plants have evolved sophisticated survival strategies to withstand inflammation, oxidative stress, microbial challenges, and environmental pressure.

EneSoothe® Repcomf Oil is powered by a synergistic blend of four botanical ingredients selected to soothe stressed skin and reinforce its natural defenses.

Artemisia annua, the natural origin of artemisinin, delivers potent anti-inflammatory and broad-spectrum antibacterial activity. Olea europaea (Olive) provides antioxidant-rich lipids that help strengthen the skin barrier and defend against oxidative stress. Matricaria chamomilla (Chamomile) helps calm irritation and support skin recovery, while Grapefruit offers antioxidant protection to help maintain healthy-looking skin exposed to daily environmental aggressors.

Key Benefits

• Helps defend skin against stress-induced irritation and inflammation

• Helps soothe redness, itching, stinging, and skin discomfort
• Supports skin barrier repair and strengthens skin resilience
• Helps reduce UV-induced skin damage
• Improves skin hydration and reduces transepidermal water loss (TEWL)
Efficacy Data

In vitro

In vivo


  • Dual Anti-Inflammatory Activity

    31.26% inhibition of COX-2 activity at 1% concentration

    43.14% inhibition of the CaN–NFAT pathway at 5 ppm


  • Barrier Repair (3D Skin Model)

    80% reduction in UV-induced sunburn cells

    60% increase in Filaggrin (FLG) expression

    97.44% increase in Loricrin (LOR) expression

    13.16% reduction in transepidermal water loss (TEWL), supporting improved skin barrier function



  • Moisturizing & Barrier Support

    28.65% increase in skin hydration after 1 hour

    21.25% reduction in TEWL after 1 hour


  • Histamine-Induced Soothing

    More than 3-fold lower histamine response score than the positive control

    Helps reduce histamine-induced redness, wheal formation, and itching, demonstrating significant soothing efficacy