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EneDefen
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  • EneDefen

EneDefen

INCI Name Citrus Grandis (Grapefruit) Fruit Extract, Lycium Chinense Root Extract, Butylene Glycol, Pentylene Glycol, Hexyldecanol
Application Anti-Aging, SPF Booster
Recommended use level 0.5~4.0%
Product Overview

EneDefen is a plant-derived photoprotective active designed to protect skin from UV-induced damage while supporting the skin’s natural defenses. Unlike conventional UV filters that only block or reflect light, EneDefen® provides multi-mechanism protection, helping reduce oxidative stress, control UV-induced pigmentation, and mitigate photo-aging.

With ultra-wide UV absorption coverage from 190–410 nm, EneDefen helps shield skin from UVC, UVB, and UVA exposure. It also enhances sunscreen performance by boosting SPF efficacy, while helping reduce erythema, sunburn, and skin darkening caused by UV exposure.

Plant Source

Rooted in traditional herbal medicine and botanical nutrition, Lycium chinense root and Citrus grandis fruit bring together centuries of plant wisdom with modern skin science. With a history of use in Asian traditional medicine for over a thousand years, Lycium chinense root has long been valued for its restorative and protective properties, helping strengthen the skin’s natural defenses and soothe UV-induced inflammation.

Complementing this heritage ingredient, Citrus grandis fruit, traditionally used as both food and medicine, is naturally rich in flavonoids and phenolic compounds. These powerful antioxidants help neutralize UV-induced oxidative stress while delivering anti-inflammatory and anti-allergic benefits.

Together, these two botanicals help protect the skin from UV-triggered damage, including oxidative stress, photo-aging, and pigmentation, while supporting long-term skin vitality and resilience.



Key Benefits

• Broad-spectrum UV protection

• Shields against UV-induced photo-aging & pigmentation

• Reduces erythema, sunburn & skin darkening

• Supports the skin’s natural defenses

• SPF booster: enhances sunscreen performance
Efficacy Data

In vitro

In vivo


  • Ultra-wide UV absorption coverage (190–410 nm), protecting against UVC, UVB & UVA

  • Significant antioxidant activity, resisting oxidative decolorization of Mauritia flexuosa oil

  • Downregulates p53 gene expression by 27%

  • Helps inhibit UV-induced pigmentation and cellular aging




  • SPF enhancement:+16–20%

  • Helps protect the skin from sunburn and erythema while reducing post-inflammatory hyperpigmentation (30 days)